Determination of Rifapentine and 25-O-desacetyl Rifapentine from 100 µl human breastmilk by LC-MS/MS using protein precipitation and solid phase extraction
There is currently no information available on the transfer of the second-line anti-TB drug, rifapentine and its metabolite, into breastmilk. The subsequent implications to the breastfed infant, as well as consequences of long-term exposure to potentially sub-therapeutic drug levels with regards to...
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| Format: | Dissertation |
| Language: | English |
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Faculty of Health Sciences
2020
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| Online Access: | https://hdl.handle.net/11427/32087 |