Interactions of quinoline antimalarials with haematin and their effect on ß-haematin formation

Includes bibliographical references. === Thermodynamic compensation in the interaction of quinoline antimalarials with haematin in 40% (v/v) aqueous OMSO has been compared with that in pure aqueous solution. The data indicate that the degree of desolvation and loss of conformational freedom is ident...

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Bibliographic Details
Main Author: Ncokazi, Kanyile K
Other Authors: Egan, Timothy J
Format: Doctoral Thesis
Language:English
Published: University of Cape Town 2014
Subjects:
Online Access:http://hdl.handle.net/11427/6350