Mechanisms of chloride modulated activity in the C-domain of angiotensin-converting enzyme
The somatic isoform of angiotensin-converting enzyme (sACE), a key regulator of blood pressure and electrolyte fluid homeostasis, primarily cleaves the hypertension-associated angiotensin-I (AngI) and bradykinin peptides, as well as a number of other physiologically relevant peptides in vitro. sACE...
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Format: | Doctoral Thesis |
Language: | English |
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University of Cape Town
2014
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Online Access: | http://hdl.handle.net/11427/6885 |