Role of neutrophil matrix metalloproteinase-9 (MMP-9) and tissue inhibitor of metalloproteases-1 (TIMP-1) in the killing of microorganisms.

Role of neutrophil matrix metalloproteinase-9 (MMP-9) and tissue inhibitor of metalloproteases-1 (TIMP-1) in the killing of microorganisms.

Microorganisms may evade killing by neutrophils (PMNs) by altering signal transduction and hence phagosome maturation. Secreted, active matrix metalloproteinases (MMPs) appear to be required for PMN killing of pseudomonas microorganisms, via an MMP and complement-dependent, but otherwise unknown mec...

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Bibliographic Details
Main Author: Ibrahim, Mukthar.
Other Authors: Elliott, Edith.
Language:en_ZA
Published: 2013
Subjects:
Neurophils.
Microorganisms.
Metalloproteinases > Antagonists and inhibitors.
Extracellular matrix.
Theses > Biochemistry.
Online Access:http://hdl.handle.net/10413/10140

Internet

http://hdl.handle.net/10413/10140

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