The role of APOBEC3G in acute and early HIV-1 subtype C infection.
Introduction APOBEC3G and other related cellular cytosine deaminase family members have potent antiviral activity. In the absence of HIV-1 Vif, APOBEC3G mutates the viral DNA during viral reverse transcription. Our knowledge of the Vif-APOBEC3G interaction in human populations infected with subtype...
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Language: | en_ZA |
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2014
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Online Access: | http://hdl.handle.net/10413/11111 |