The role of APOBEC3G in acute and early HIV-1 subtype C infection.

Introduction APOBEC3G and other related cellular cytosine deaminase family members have potent antiviral activity. In the absence of HIV-1 Vif, APOBEC3G mutates the viral DNA during viral reverse transcription. Our knowledge of the Vif-APOBEC3G interaction in human populations infected with subtype...

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Bibliographic Details
Main Author: Reddy, Kavidha.
Other Authors: Winkler, Cheryl A.
Language:en_ZA
Published: 2014
Subjects:
Online Access:http://hdl.handle.net/10413/11111