Synthesis of tetrahydroisoquinoline (TIQ) ligands and their applications in ayymmetric catalysis.
A series of 88 novel tetrahydroisoquinoline (TIQ) compounds have been synthesised for applications in asymmetric catalysis. Several chiral TIQ ligands, possessing N,O and N,N donor atoms, have been prepared and evaluated for the catalytic asymmetric transfer hydrogenation (ATH) of pro-chiral ketones...
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| Language: | en |
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2012
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| Online Access: | http://hdl.handle.net/10413/6190 |