The possible implication of selected Fusarium Mycotoxins in the aetiology of brain cancer.
The central nervous system is a potential site of action for the Fusarium mycotoxin Fumonisin B1 (FB1), and is exemplified in horses by the disease equine leukoencephalomalacia. Structurally resembling sphingoid bases, FB1 inhibits ceramide synthase, an enzyme involved in sphingolipid metabolism, le...
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| Language: | en_ZA |
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2012
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| Online Access: | http://hdl.handle.net/10413/6333 |