Neutralizing antibody responses and viral evolution in a longitudinal cohort of HIV subtype C infected antiretroviral-naïve individuals.

Background: HIV-1 envelope (Env) diversity is arguably the most significant challenge for the development of an efficacious vaccine. An ideal vaccine would elicit the production of broadly neutralizing antibodies (nAb), capable of retaining potent activity against a diverse panel of viral isolates....

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Bibliographic Details
Main Author: Archary, Derseree.
Other Authors: Coovadia, Hoosen Mahomed.
Language:en_ZA
Published: 2013
Subjects:
Online Access:http://hdl.handle.net/10413/8701