The toxicity and therapeutic index of a methotrexate polymeric compound, D-85

Methotrexate (MTX) has been used for many years in the treatment of patients with cancer as a cytotoxic agent and as an anti-inflammatory drug for the treatment of inflammatory diseases, such as rheumatoid arthritis (RA). However, because of the side effects associated with MTX, there is a continuou...

Full description

Bibliographic Details
Main Author: Visser, Suzaan
Other Authors: Prof C E Medlen
Published: 2013
Subjects:
Online Access:http://hdl.handle.net/2263/24575
http://upetd.up.ac.za/thesis/available/etd-05122008-133405/