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In vitro cell signaling events of 2-methoxyestradiol-bis-sulphamate in a breast adenocarcinoma- and a non-tumorigenic breast epithelial cell line

In vitro cell signaling events of 2-methoxyestradiol-bis-sulphamate in a breast adenocarcinoma- and a non-tumorigenic breast epithelial cell line

2-Methoxyestradiol, an endogenous metabolite of 17-β-estradiol exerts antipropliferative, antiangiogenic and antitumor effects in vitro and in vivo and is currently in clinical trials phase II for various types of cancers including breast cancer. Due to low oral bioavailability and rapid metabolic d...

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Bibliographic Details
Main Author: Visagie, M.H. (Michelle Helen)
Other Authors: Joubert, Annie M.
Published: 2013
Subjects:
2-meoe2bismate
Autophagy
Mcf-12a
Apoptosis
Mcf-7
UCTD
Online Access:http://hdl.handle.net/2263/26210
Visagie, MH 2010, In vitro cell signaling events of 2-methoxyestradiol-bis-sulphamate in a breast adenocarcinoma- and a non-tumorigenic breast epithelial cell line, MSc dissertation, University of Pretoria, Pretoria, viewed yymmdd < http://hdl.handle.net/2263/26210 >
http://upetd.up.ac.za/thesis/available/etd-07112011-123356/
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Internet

http://hdl.handle.net/2263/26210
Visagie, MH 2010, In vitro cell signaling events of 2-methoxyestradiol-bis-sulphamate in a breast adenocarcinoma- and a non-tumorigenic breast epithelial cell line, MSc dissertation, University of Pretoria, Pretoria, viewed yymmdd < http://hdl.handle.net/2263/26210 >
http://upetd.up.ac.za/thesis/available/etd-07112011-123356/

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