In vitro antiplasmodial activity of an optimised series of alkylated (bis)urea and (bis)thiourea polyamine analogs

In vitro antiplasmodial activity of an optimised series of alkylated (bis)urea and (bis)thiourea polyamine analogs

The malaria parasite, Plasmodium falciparum, exhibits genetic plasticity such that it increasingly develops resistance to current antimalarial drugs, especially in Southeast Asia where multi-drug resistance (MDR) threatens the last line of antimalarial drugs (1, 2). This obstructs the effectiveness...

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Bibliographic Details
Main Author: De Beer, Marna
Other Authors: Birkholtz, Lyn-Marie
Language:en
Published: University of Pretoria 2014
Subjects:
Biochemistry
UCTD
Online Access:http://hdl.handle.net/2263/36823
De Beer, M 2013, In vitro antiplasmodial activity of an optimised series of alkylated (bis)urea and (bis)thiourea polyamine analogs, MSc Dissertation, University of Pretoria, Pretoria, viewed yymmdd <http://hdl.handle.net/2263/36823>

Internet

http://hdl.handle.net/2263/36823
De Beer, M 2013, In vitro antiplasmodial activity of an optimised series of alkylated (bis)urea and (bis)thiourea polyamine analogs, MSc Dissertation, University of Pretoria, Pretoria, viewed yymmdd <http://hdl.handle.net/2263/36823>

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