Tacrine, trolox and tryptoline as lead compounds for the design and synthesis of multi-target drugs for Alzheimer's disease therapy

Magister Pharmaceuticae - MPharm === The cascade of neurotoxic events involved in the pathogenesis of Alzheimer's disease may explain the inefficacy of currently available treatment based on acetylcholinesterase inhibitors (AChEI - donepezil, galantamine, rivastigmine) and N-methyl-D-aspartate...

Full description

Bibliographic Details
Main Author: Teponnou, Gerard A. Kenfack
Other Authors: Malan, Sarel F.
Language:en
Published: University of the Western Cape 2016
Subjects:
Online Access:http://hdl.handle.net/11394/5344