The role of a conserved interdomain salt bridge on the structure, function and stability of the Y-GSTs
Domain interfaces are important to the folding, stability, structure and function of multidomain proteins. In the case of human glutathione S-transferase A1-1 (hGSTA1-1) site-directed mutagenesis studies have previously implicated the interdomain Arg13 residue of the protein in maintaining the prope...
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Format: | Others |
Language: | en |
Published: |
2013
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Online Access: | http://hdl.handle.net/10539/12315 |