Telomere dynamics in chronic myeloid leukaemia

Telomeres are regions of tandem repeats at the ends of chromosomes ensuring chromosome stability or inducing replicative senescence when critically short. Telomerase extends telomeres and its catalytic subunit, telomerase reverse transcriptase is tightly regulated at multiple levels. Cancerous cells...

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Bibliographic Details
Main Author: Gil, Marcel Eduardo
Format: Others
Language:en
Published: 2014
Subjects:
Online Access:http://hdl.handle.net10539/14039