Evaluation of the NIH clinical collection to identify potential HIV-1 integrase inhibitors
HIV-1 integrase is an essential enzyme in the HIV replication cycle and is a validated target for antiretroviral drugs. Due to the inevitable emergence of drug resistance of HIV-1 strains to all currently approved FDA antiretroviral drugs, antivirals with new mechanisms of action are continuously in...
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| Format: | Others |
| Language: | en |
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2014
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| Online Access: | http://hdl.handle.net/10539/15448 |