Robust sequence alignment using evolutionary rates coupled with an amino acid substitution matrix

Selective pressures at the DNA level shape genes into pro les consisting of patterns of rapidly evolving sites and sites withstanding change. These pro les remain detectable even when protein sequences become extensively diverged. It has been hypothesised that these patterns can be used as gene i...

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Bibliographic Details
Main Author: Ndhlovu, Andrew
Format: Others
Language:en
Published: 2015
Subjects:
Online Access:http://hdl.handle.net/10539/18660