Robust sequence alignment using evolutionary rates coupled with an amino acid substitution matrix
Selective pressures at the DNA level shape genes into pro les consisting of patterns of rapidly evolving sites and sites withstanding change. These pro les remain detectable even when protein sequences become extensively diverged. It has been hypothesised that these patterns can be used as gene i...
Main Author: | |
---|---|
Format: | Others |
Language: | en |
Published: |
2015
|
Subjects: | |
Online Access: | http://hdl.handle.net/10539/18660 |