Short hairpin RNA-directed knockdown of epidermal growth factor receptor in human oesophageal squamous carcinoma cell lines
Epidermal growth factor receptor (EGFR) is a transmembrane receptor tyrosine kinase which activates, upon EGFR binding, a number of signaling pathways including the mitogenic protein kinase pathway (MAPK) and phosphatidylinositol 3-kinase cascade (PI3K). Over expression of EGFR is a common featur...
| Main Author: | |
|---|---|
| Format: | Others |
| Language: | en |
| Published: |
2008
|
| Subjects: | |
| Online Access: | http://hdl.handle.net/10539/4896 |