Mikrokalorimetrické studium termodynamické stability hybridních komplexů nukleových kyselin
This work deals with implementation of differential scanning kalorimetry (DSC) into research of potential oligonucleotide therapeutics. Capabilities and limits of the DSC device have been determined and optimal conditions for measurement of nucleic acids complexes specified. Four types of modified o...
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Format: | Dissertation |
Language: | Czech |
Published: |
2009
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Online Access: | http://www.nusl.cz/ntk/nusl-277970 |