Identifikace peptidického konjugátu s toxickým metabolitem paracetamolu N-acetyl-p-benzochinon iminem
Acetaminophen (paracetamol) is one of the most used analgesic drug. It is considered as a safe drug, although its administration in large doses can lead to due to known metabolism to impairment of hepatocytes with subsequent necrosis. Acetaminophen is metabolized primarily in the liver where it is c...
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Format: | Dissertation |
Language: | English |
Published: |
2010
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Online Access: | http://www.nusl.cz/ntk/nusl-279071 |