Mechanizmy vzniku rezistence vůči platinovým cytostatikům
1. Abstract Although the first platinum drug cisplatin was initially described in 1845, its biological activity was discovered more than 100 years later. Since then are cisplatin and its clinically used analogues carboplatin and oxaliplatin in widespread use for the treatment of variety of human can...
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Format: | Dissertation |
Language: | English |
Published: |
2009
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Online Access: | http://www.nusl.cz/ntk/nusl-282901 |