Mikrosatelitová nestabilita u pacientů s hereditárním nepolypózním kolorektálním karcinomem
Detection of microsatellite instability (MSI) is the standard part of mutational analysis in hereditary nonpolyposis colorectal cancers (HNPCC). Characteristic phenotypic feature of MSI indicates loss of mismatch repair (MMR) in tumor cells. We studied MSI in 205 tumors from 152 patients with HNPCC....
| Main Author: | |
|---|---|
| Other Authors: | |
| Format: | Doctoral Thesis |
| Language: | Czech |
| Published: |
2007
|
| Online Access: | http://www.nusl.cz/ntk/nusl-288689 |