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In human cells ribosomal genes are organized as clusters called Nucleolus Organizer Regions (NORs) that are situated on the short arms of acrocentric chromosomes. It was found that essential components of the RNA polymerase I transcription machinery, including Upstream Binding Factor (UBF), can be d...

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Bibliographic Details
Main Author: Kalmárová, Markéta
Other Authors: Raška, Ivan
Format: Doctoral Thesis
Language:English
Published: 2008
Online Access:http://www.nusl.cz/ntk/nusl-292949