Výpočetní studie interakcí organokovových komplexů s modely DNK/RNK a proteinů s využitím nástrojů kvantové chemie a molekulové mechaniky .
Methods of computational chemistry represent an important tool in development of novel materials or drugs. In this thesis, they are used for investigation of Pt anticancer drugs. Interaction of five hydrated Pt(II) complexes with guanine as a small model of DNA is studied at the DFT level. Several P...
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| Format: | Doctoral Thesis |
| Language: | English |
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2017
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| Online Access: | http://www.nusl.cz/ntk/nusl-369537 |