Mitochondriální protein 17β-hydroxysteroidová dehydrogenáza typu 10 v mozku genetického animálního modelu Alzheimerovy choroby (potkani McGill-R-Thy1-APP)
Transgenic McGill-R-Thy1-APP rats are one of the best animal genetic models of Alzheimer's disease (AD). Significant intracellular elevation of soluble amyloid β (Aβ) and cognitive deficits are observed already in 3-month-old rats, prior to extracellular plaque deposition. Mitochondrial bioener...
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Format: | Dissertation |
Language: | Czech |
Published: |
2018
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Online Access: | http://www.nusl.cz/ntk/nusl-380209 |