All-trans retinoic acid-induced apoptosis in acute myeloblastic leukemia cells:with a special emphasis on p53, Bcl-2, and mitochondria
Abstract All-trans retinoic acid (ATRA) is a derivative of vitamin A. It is able to stimulate neutrophilic differentiation of normal progenitors and acute promyelocytic leukemia (APL) cells. Although ATRA-induced differentiation is not observed in any other acute myeloblastic leukemia (AML) subtype...
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| Format: | Doctoral Thesis |
| Language: | English |
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Oulun yliopisto
2000
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| Online Access: | http://urn.fi/urn:isbn:9514256735 http://nbn-resolving.de/urn:isbn:9514256735 |