Human lysyl hydroxylase:identification of the residue involved in the binding of 2-oxoglutarate at the catalytic site and characterization of a novel isoenzyme, LH3, and its gene

Abstract Lysyl hydroxylase (E.C. 1.14.11.4, protocollagen-lysine 2-oxoglutarate 5-dioxygenase, PLOD) catalyses the formation of hydroxylysine in collagens and other proteins with collagen-like sequences. The hydroxylysine residues participate in the formation of collagen crosslinks and serve as att...

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Bibliographic Details
Main Author: Passoja, K. (Kaisa)
Format: Doctoral Thesis
Language:English
Published: Oulun yliopisto 2000
Subjects:
Online Access:http://urn.fi/urn:isbn:9514257324
http://nbn-resolving.de/urn:isbn:9514257324