Recombinant human collagens:characterization of type II collagen expressed in insect cells and production of types I-III collagen in the yeast <em>Pichia pastoris</em>
Abstract An efficient system for expressing recombinant human collagens is expected to have numerous scientific and medical applications, but this is difficult to achieve because most systems do not have sufficient levels of activity of prolyl 4-hydroxylase, the key enzyme of collagen synthesis....
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Format: | Doctoral Thesis |
Language: | English |
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University of Oulu
2000
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Online Access: | http://urn.fi/urn:isbn:9514257383 http://nbn-resolving.de/urn:isbn:9514257383 |