Lysyl oxidases:cloning and characterization of the fourth and the fifth human lysyl oxidase isoenzymes, and the consequences of a targeted inactivation of the first described lysyl oxidase isoenzyme in mice
Abstract Lysyl oxidases (EC 1.4.3.13, protein-lysine 6-oxidases) are extracellular copper enzymes that initiate the cross-linking of collagens and elastin by catalyzing oxidative deamination of the ε-amino group in certain lysine and hydroxylysine residues. The cross-links formed are responsible fo...
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| Format: | Doctoral Thesis |
| Language: | English |
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University of Oulu
2002
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| Online Access: | http://urn.fi/urn:isbn:9514267397 http://nbn-resolving.de/urn:isbn:9514267397 |