Characterization of the novel human prolyl 4-hydroxylases and asparaginyl hydroxylase that modify the hypoxia-inducible factor
Abstract HIF prolyl 4-hydroxylases (HIF-P4Hs) and HIF asparaginyl hydroxylase (FIH) are novel members of the 2-oxoglutarate dioxygenase family that play key roles in the regulation of the hypoxia-inducible transcription factor (HIF). They hydroxylate specific proline and asparagine residues in HIF-...
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| Format: | Doctoral Thesis |
| Language: | English |
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University of Oulu
2004
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| Online Access: | http://urn.fi/urn:isbn:9514275756 http://nbn-resolving.de/urn:isbn:9514275756 |