Expression and analysis of recombinant human collagen prolyl 4-hydroxylase in <em>E. coli</em> and optimization of expression
Abstract Collagen prolyl 4-hydroxylase (C-P4H) plays a central role in the biosynthesis of collagens by hydroxylating proline residues. The enzyme has been a subject of intense interest as a target enzyme for drug development. The recombinant expression of human C-P4H in prokaryotes has not yet bee...
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| Format: | Doctoral Thesis |
| Language: | English |
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University of Oulu
2006
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| Online Access: | http://urn.fi/urn:isbn:9514281063 http://nbn-resolving.de/urn:isbn:9514281063 |