Enzymes involved in hypoxia response:characterization of the <em>in vivo</em> role of HIF-P4H-2 in mouse heart, of a novel P4H in human and zebrafish and of the catalytic properties of FIH
Abstract Oxygen homeostasis is critical to all animals, as both excess (hyperoxia) and reduced (hypoxia) levels of oxygen can result in pathological changes and ultimately in the loss of cellular and organismal viability. Complex systems have evolved to sense and adapt to changes in cellular oxy...
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| Format: | Doctoral Thesis |
| Language: | English |
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University of Oulu
2010
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| Online Access: | http://urn.fi/urn:isbn:9789514261947 http://nbn-resolving.de/urn:isbn:9789514261947 |