Molecular genetics of early-onset Alzheimer's disease and frontotemporal lobar degeneration
Abstract Alzheimer's disease (AD) and frontotemporal lobar degeneration (FTLD) are the two most common neurodegenerative diseases leading to early onset dementia (< 65 years). Mutations in the amyloid precursor protein (APP), presenilin 1 (PSEN1) and presenilin 2 (PSEN2) genes cause a p...
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Format: | Doctoral Thesis |
Language: | English |
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University of Oulu
2010
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Online Access: | http://urn.fi/urn:isbn:9789514263156 http://nbn-resolving.de/urn:isbn:9789514263156 |