Molecular genetics of early-onset Alzheimer's disease and frontotemporal lobar degeneration

Abstract Alzheimer's disease (AD) and frontotemporal lobar degeneration (FTLD) are the two most common neurodegenerative diseases leading to early onset dementia (< 65 years). Mutations in the amyloid precursor protein (APP), presenilin 1 (PSEN1) and presenilin 2 (PSEN2) genes cause a p...

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Bibliographic Details
Main Author: Krüger, J. (Johanna)
Format: Doctoral Thesis
Language:English
Published: University of Oulu 2010
Subjects:
Online Access:http://urn.fi/urn:isbn:9789514263156
http://nbn-resolving.de/urn:isbn:9789514263156