Mechanism of action of the glutaredoxins and their role in human lung diseases
Abstract Glutaredoxins (Grx) are small thiol disulphide oxidoreductases with a conserved active site sequence -CXXC/S- and a glutathione (GSH) binding site. They catalyze the reduction of protein disulphides, preferring protein-GSH mixed disulphides as substrates. The accumulation of protein-GSH mi...
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| Format: | Doctoral Thesis |
| Language: | English |
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University of Oulu
2007
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| Online Access: | http://urn.fi/urn:isbn:9789514285165 http://nbn-resolving.de/urn:isbn:9789514285165 |