Prolyl 3-hydroxylases and hypoxia-inducible factor 3:their roles in collagen synthesis and hypoxia response, respectively

Abstract Collagens are subject to extensive post-translational modifications, including the formation of 4-hydroxyproline, 3-hydroxyproline and hydroxylysine. These reactions are catalyzed by collagen prolyl 4-hydroxylases (C-P4Hs), prolyl 3-hydroxylases (P3Hs) and lysine hydroxylases (LHs), which b...

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Bibliographic Details
Main Author: Pasanen, A. (Annika)
Other Authors: Myllyharju, J. (Johanna)
Format: Doctoral Thesis
Language:English
Published: Oulun yliopisto 2011
Subjects:
Online Access:http://urn.fi/urn:isbn:9789514294594
http://nbn-resolving.de/urn:isbn:9789514294594