Prolyl 4-hydroxylases, key enzymes regulating hypoxia response and collagen synthesis:the roles of specific isoenzymes in the control of erythropoiesis and skeletogenesis
Abstract Oxygen deprivation (hypoxia) is related to many disease conditions, such as anemia, but is also a critical regulatory signal during normal development. Cellular responses to hypoxia are largely mediated through alterations in gene regulation brought about by the transcription factor known...
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| Format: | Doctoral Thesis |
| Language: | English |
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Oulun yliopisto
2013
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| Online Access: | http://urn.fi/urn:isbn:9789526200835 http://nbn-resolving.de/urn:isbn:9789526200835 |