Analyses of kidney organogenesis through <em>in vitro</em> and <em>in vivo</em> approaches:generation of conditional Wnt4 mouse models and a method for applying inducible Cre-recombination for kidney organ culture
Abstract In mice, gene targeting has become a useful tool for resolving the functions of proteins and for creating new animal models. Cre/loxP technology has been used broadly for generation of genetically modified mice. The Cre recombinase recognizes a specific DNA sequence, called loxP, and remove...
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| Format: | Doctoral Thesis |
| Language: | English |
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Oulun yliopisto
2013
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| Online Access: | http://urn.fi/urn:isbn:9789526201559 http://nbn-resolving.de/urn:isbn:9789526201559 |