Hypoxia-inducible factor prolyl 4-hydroxylases regulating erythropoiesis, and hypoxia-inducible lysyl oxidase regulating skeletal muscle development during embryogenesis
Abstract Erythropoiesis is the process of red blood cell production. The main regulator is the erythropoietin (EPO) hormone, which is strongly upregulated in low oxygen concentration (hypoxia) in cells via the hypoxia-inducible transcription factor HIF. The stability of HIF is regulated in an oxygen...
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Format: | Doctoral Thesis |
Language: | English |
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Oulun yliopisto
2014
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Online Access: | http://urn.fi/urn:isbn:9789526206943 http://nbn-resolving.de/urn:isbn:9789526206943 |