Preparation of amorphous forms to increase the solubility of poorly soluble drugs using spray drying
Spray drying is widely used in enhancing the aqueous solubility of poorly soluble compounds. In this study, the mechanism of solubility enhancement was characterized using three model drugs-naproxen, ketoprofen and furosemide. Physical mixtures of the model drug with polyvinylpyrrolidine and spray d...
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| Format: | Others |
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Scholarly Commons
2011
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| Online Access: | https://scholarlycommons.pacific.edu/uop_etds/274 https://scholarlycommons.pacific.edu/cgi/viewcontent.cgi?article=1273&context=uop_etds |