Evaluation of bootstrapping as a validation technique for population pharmacokinetic models

It has been recommended by the FDA and others that the population pharmacokinetic models (PPKM) need to be validated. This is particularly true when the model plays a key role in the construction of dosing strategies. It was the objective of the current study to evaluate the ability of bootstrapping...

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Bibliographic Details
Main Author: Al-otoum, Mohammed Fawzi
Format: Others
Published: Scholarly Commons 2004
Subjects:
Online Access:https://scholarlycommons.pacific.edu/uop_etds/590
https://scholarlycommons.pacific.edu/cgi/viewcontent.cgi?article=1589&context=uop_etds