Determination of solution structure of anti-cancer drug etoposide by NMR and computer simulation
2.9 mM etoposide in CDCl3 and CDCl3/(D20) were studied at 300 and 500 MHz NMR. One dimensional (1D) NMR spectra and truncated lD Nuclear Overhauser Effect (NOE) buildup experiments were used to find direct information on the structure of etoposide. Results showed that the E-ring rotates freely about...
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| Format: | Others |
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Scholarly Commons
1997
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| Online Access: | https://scholarlycommons.pacific.edu/uop_etds/2323 https://scholarlycommons.pacific.edu/cgi/viewcontent.cgi?article=3322&context=uop_etds |