Characterization of the roles of PPP1R15A (GADD34) and PPP1R15B (CReP) in ER stress-induced apoptosis in vivo
Failure to balance synthesis, folding and degradation of secreted proteins results in the accumulation of unfolded proteins in the endoplasmic reticulum, termed ER stress. Cells respond to ER stress by activating a signaling pathway known as the unfolded protein response (UPR). The UPR induces phosp...
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| Format: | Others |
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Scholarly Commons
2019
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| Online Access: | https://scholarlycommons.pacific.edu/uop_etds/3616 https://scholarlycommons.pacific.edu/cgi/viewcontent.cgi?article=4616&context=uop_etds |