Development of a new class of ligand-targeted chemotherapeutics with enhanced safety and efficacy profile
The hydrophobicity of many chemotherapeutic agents usually results in their nonselective passive distribution into healthy cells and organs causing collateral toxicity. Ligand-targeted drugs (LTDs) are a promising class of targeted anticancer agents. The hydrophilicity of the targeting ligands in...
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Scholarly Commons
2019
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Online Access: | https://scholarlycommons.pacific.edu/uop_etds/3642 https://scholarlycommons.pacific.edu/cgi/viewcontent.cgi?article=4640&context=uop_etds |