Discovery and Characterization of the Proteins Involved in the Synthesis of N⁶-Threonylcarbamoyl Adenosine, a Nucleoside Modification of tRNA

N6-threonylcarbamoyl adenosine (t6A) is a universally conserved tRNA modification found at position 37 of tRNAs which decode ANN codons. Structural studies have implicated its presence as a requirement for the disruption of a U-turn motif in certain tRNAs, leading to the formation of properly struct...

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Bibliographic Details
Main Author: Deutsch, Christopher Wayne
Format: Others
Published: PDXScholar 2016
Subjects:
Online Access:http://pdxscholar.library.pdx.edu/open_access_etds/3080
http://pdxscholar.library.pdx.edu/cgi/viewcontent.cgi?article=4090&context=open_access_etds