Novel Compound, 84F2, Inhibits Calmodulin Deficient RyR2
The cardiac ryanodine receptor (RyR2) plays a key role in excitation-contraction coupling (ECC). Mutations in RyR2 are known to be linked to the arrhythmogenic disorder, catecholaminergic polymorphic ventricular tachycardia (CPVT), a deadly disease which is characterized by a leak of calcium from sa...
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| Format: | Others |
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PDXScholar
2017
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| Online Access: | https://pdxscholar.library.pdx.edu/open_access_etds/3484 https://pdxscholar.library.pdx.edu/cgi/viewcontent.cgi?article=4493&context=open_access_etds |