MITOCHONDRIAL DNA COPY NUMBER AND AUTOPHAGY IN THE AGING BRAIN AND IN AN ALZHEIMER MOUSE MODEL
Decreased mitochondrial function is associated with aging and is an early step in Alzheimer's disease (AD). Autophagy also declines with age and is required for degradation of dysfunctional mitochondria but it is not known whether autophagosomal formation is overactive and/or degradation of au...
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| Format: | Others |
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OpenSIUC
2014
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| Online Access: | https://opensiuc.lib.siu.edu/dissertations/913 https://opensiuc.lib.siu.edu/cgi/viewcontent.cgi?article=1916&context=dissertations |