MITOCHONDRIAL DNA COPY NUMBER AND AUTOPHAGY IN THE AGING BRAIN AND IN AN ALZHEIMER MOUSE MODEL

MITOCHONDRIAL DNA COPY NUMBER AND AUTOPHAGY IN THE AGING BRAIN AND IN AN ALZHEIMER MOUSE MODEL

Decreased mitochondrial function is associated with aging and is an early step in Alzheimer's disease (AD). Autophagy also declines with age and is required for degradation of dysfunctional mitochondria but it is not known whether autophagosomal formation is overactive and/or degradation of au...

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Bibliographic Details
Main Author:	Barnett, Aaron
Format:	Others
Published:	OpenSIUC 2014
Subjects:	aging Alzheimer's Disease autophagy mitochondrial
Online Access:	https://opensiuc.lib.siu.edu/dissertations/913 https://opensiuc.lib.siu.edu/cgi/viewcontent.cgi?article=1916&context=dissertations

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