LOSS OF RAB25 COOPERATES WITH ONCOGENES IN THE TRANSFORMATION OF HUMAN MAMMARY EPITHELIAL CELLS (HMEC)

The RAB guanosine triphosphates (RAS-related in brain) belong to the Ras superfamily of GTPases, and loss of RAB 25 expression has been reported in a number of breast cancer cases containing H-Ras point mutations, particularly triple negative breast cancers (TNBC), one of the most aggressive subtype...

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Bibliographic Details
Main Author: Sridhar Joshi, Pooja
Format: Others
Published: OpenSIUC 2017
Subjects:
Online Access:https://opensiuc.lib.siu.edu/theses/2150
https://opensiuc.lib.siu.edu/cgi/viewcontent.cgi?article=3164&context=theses