Mechanisms of aryl hydrocarbon receptor and estrogen receptor action in breast cancer cells

In MCF7 and T47D cells cotreated with 1 nM 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) plus 0.1-10 μM 3’,4’-dimethoxy flavone (DMF), there was a concentration-dependent decrease in the TCDD-induced ethoxyresorufin O-deethylase (EROD) activity. Gel mobility shift assays showed that 3’,4’-...

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Bibliographic Details
Main Author: Lee, Jeong Eun
Other Authors: Safe, Stephen H.
Format: Others
Language:en_US
Published: Texas A&M University 2006
Subjects:
AhR
ER
Online Access:http://hdl.handle.net/1969.1/3109