Evaluation of unmarked deletion mutants as improved Brucella vaccine strains in the mouse and goat models

Historical data suggests that prolonged survival of Brucella vaccine organisms in the target host enhances immune protection. Recent research has focused upon the development of rough vaccine strains to avoid interference with standard diagnostic tests. Rough organisms are rapidly cleared from the h...

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Bibliographic Details
Main Author: Kahl, Melissa Marie
Other Authors: Ficht, Thomas A.
Format: Others
Language:en_US
Published: Texas A&M University 2006
Subjects:
Online Access:http://hdl.handle.net/1969.1/4197