Evaluation of unmarked deletion mutants as improved Brucella vaccine strains in the mouse and goat models
Historical data suggests that prolonged survival of Brucella vaccine organisms in the target host enhances immune protection. Recent research has focused upon the development of rough vaccine strains to avoid interference with standard diagnostic tests. Rough organisms are rapidly cleared from the h...
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Format: | Others |
Language: | en_US |
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Texas A&M University
2006
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Online Access: | http://hdl.handle.net/1969.1/4197 |