Directed evolution of phosphotriesterase for detoxification of the nerve agent VX

Phosphotriesterase (PTE) isolated from the soil bacterium Flavobacterium sp. is a member of the amidohydrolase superfamily. PTE catalyzes the hydrolysis of a broad spectrum of organophosphate triesters including the insecticide paraoxon, and the chemical warfare agents; GF, sarin, and soman. In addi...

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Bibliographic Details
Main Author: Ghanem, Eman Mohamed
Other Authors: Raushel, Frank M.
Format: Others
Language:en_US
Published: Texas A&M University 2006
Subjects:
Online Access:http://hdl.handle.net/1969.1/4330